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Why does my blood count keep getting low?

Diseases and conditions that cause your body to produce fewer red blood cells than normal include: Aplastic anemia. Cancer. Certain medications, such as antiretroviral drugs for HIV infection and chemotherapy drugs for cancer and other conditions.

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Normally low hemoglobin counts

A slightly low hemoglobin count isn't always a sign of illness — it can be normal for some people. Women with menstrual periods and pregnant women commonly have low hemoglobin counts.

Low hemoglobin counts associated with diseases and conditions

A low hemoglobin count can be associated with a disease or condition that causes your body to have too few red blood cells. This can occur if: Your body produces fewer red blood cells than usual Your body destroys red blood cells faster than they can be produced You have blood loss Diseases and conditions that cause your body to produce fewer red blood cells than normal include: Diseases and conditions that cause your body to destroy red blood cells faster than they can be made include: A low hemoglobin count can also be due to blood loss, which can occur because of: Bleeding in your digestive tract, such as from ulcers, cancers or hemorrhoids Frequent blood donation Menorrhagia (heavy menstrual bleeding) (heavy menstrual bleeding-although even normal menstrual bleeding may cause a slightly low hemoglobin count) Causes shown here are commonly associated with this symptom. Work with your doctor or other health care professional for an accurate diagnosis. There is a problem with information submitted for this request. Review/update the information highlighted below and resubmit the form. From Mayo Clinic to your inbox Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. Email ErrorEmail field is required ErrorInclude a valid email address Learn more about Mayo Clinic’s use of data. To provide you with the most relevant and helpful information, and understand which information is beneficial, we may combine your email and website usage information with other information we have about you. If you are a Mayo Clinic patient, this could include protected health information. If we combine this information with your protected health information, we will treat all of that information as protected health information and will only use or disclose that information as set forth in our notice of privacy practices. You may opt-out of email communications at any time by clicking on the unsubscribe link in the e-mail. Subscribe! Thank you for subscribing! You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry

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What builds red blood cells?

Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow are called hemocytoblasts. They give rise to all of the formed elements in blood. If a stem cell commits to becoming a cell called a proerythroblast, it will develop into a new red blood cell.

Overview

Blood has been called the river of life, transporting various substances that must be carried to one part of the body or another. Red blood cells are an important element of blood. Their job is to transport oxygen to the body's tissues in exchange for carbon dioxide, which they carry to the lungs to be expelled. Red blood cells are formed in the red bone marrow of bones. Stem cells in the red bone marrow are called hemocytoblasts. They give rise to all of the formed elements in blood. If a stem cell commits to becoming a cell called a proerythroblast, it will develop into a new red blood cell. The formation of a red blood cell takes about 2 days. The body makes about two million red blood cells every second! Blood is made up of both cellular and liquid components. If a sample of blood is spun in a centrifuge, the formed elements and fluid matrix of blood can be separated from each other. Blood consists of 45% red blood cells, less than 1% white blood cells and platelets, and 55% plasma.

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