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When should I take effervescent?

Adults: 1 effervescent tablet once daily. Patients who have difficulty coughing up phlegm (elderly and weakened patients), are advised to take the effervescent tablet in the mornings. Dissolve the effervescent tablet in half a glass of water.

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NACSYS 600mg Effervescent Tablets

1. What NACSYS 600 mg effervescent tablets are and what they are used for 2. What you need to know before you use NACSYS 600 mg effervescent tablets 3. How to use NACSYS 600 mg effervescent tablets 4. Possible side effects 5. How to store NACSYS 600 mg effervescent tablets 6. Other information

What is in this leaflet

NACSYS 600 mg Effervescent tablets are indicated only for adults.

Acetylcysteine is used in the treatment of airway diseases such as bronchitis (inflammation of the mucous membranes in the airways), emphysema, mucoviscidosis (cystic fibrosis) and bronchiectasis (chronic widening of an airway passage). Acetylcysteine breaks down and loosens thick phlegm, making it runny and easy to cough up. 1. WHAT NACSYS 600 MG EFFERVESCENT TABLETS ARE AND WHAT THEY ARE USED FOR This medicinal product contains 115 mg sodium per dose. To be taken into consideration by patients on a controlled sodium diet.

Ingredients of this medicine you should take into account

There are no data available on the effect of acetylcysteine on the ability to drive. An effect is, however, not likely. If you are pregnant or breast-feeding, contact your doctor or pharmacist before using any medicine. It is not known whether acetylcysteine is excreted in breast milk. Only use NACSYS 600 mg effervescent tablets after careful consideration of the benefits and risks during breast-feeding. Animal studies do not indicate direct or indirect harmful effects on the pregnancy, or the development of the child, before, during or after birth. Only use NACSYS 600 mg effervescent tablets after careful consideration of the benefits and risks during pregnancy. There is a limited amount of data from the use of acetylcysteine in pregnant women. Tell your doctor or pharmacist if you are taking or have recently taken any other medicines apart from NACSYS 600 mg effervescent tablets, including medicines obtained without a prescription. If you use activated charcoal (a medicine against traveller's diarrhoea), it may decrease the effect of NACSYS 600 mg effervescent tablets. NACSYS 600 mg effervescent tablets may increase the blood pressure-lowering effect of nitroglycerin (a medicine used against tight painful feeling in the chest (angina pectoris)). Caution is advised.

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Cough suppressants should not be used at the same time as NACSYS 600 mg effervescent tablets, as you must be able to cough up the loosened phlegm. If you need to use medicines to control or prevent infections (antibiotics), you are advised to take these two hours before or after NACSYS 600 mg effervescent tablets. If you are using other medicines, do not dissolve them together with NACSYS 600 mg effervescent tablets. Consult your doctor if any of the above mentioned warnings apply to you, or have applied to you in the past. 2. WHAT YOU NEED TO KNOW BEFORE YOU USE NACSYS 600 MG EFFERVESCENT TABLETS If you have forgotten to take a dose and it is almost time for the next dose, do not take the 'forgotten' dose, but continue the schedule as given under "How to use NACSYS 600 mg effervescent tablets ". Do not take a double dose to make up for a forgotten dose.

If you forget to take NACSYS 600 mg effervescent tablets

If you have used too many NACSYS 600 mg effervescent tablets, immediately contact your doctor or pharmacist.

Symptoms that may occur are: nausea, vomiting and diarrhoea.

If you use more NACSYS 600 mg effervescent tablets than you should

Do not use this medicine for longer than 14 days without consulting a doctor. Always use this medicine exactly as prescribed. Check with your doctor or pharmacist if you are not sure. Dissolve the effervescent tablet in half a glass of water. Drink the solution immediately. Patients who have difficulty coughing up phlegm (elderly and weakened patients), are advised to take the effervescent tablet in the mornings.

4. POSSIBLE SIDE EFFECTS

If any of the following side effects occur, immediately stop using NACSYS 600 mg effervescent tablets and contact your doctor or go the emergency room of a nearby hospital. Shock (severe drop in blood pressure, paleness, restlessness, weak pulse, clammy skin, decreased consciousness) due to a sudden widening of the blood vessels as a result of severe hypersensitivity to certain ingredients (anaphylactic shock).

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Sudden fluid accumulation in the skin and mucous membranes (e.g. throat or tongue), breathing difficulties and/or itching and skin rash, often as a result of an allergic reaction (angioedema). The above mentioned reactions are very serious side effects. If you experience any of these reactions it is possible that you have a hypersensitivity reaction to NACSYS 600 mg effervescent tablets. You will require emergency medical care or need to be admitted to hospital. This very serious side effect is very rare (occurs in fewer than 1 in 10,000 users). Bleedings are also very rare.

Inform your doctor if you experience any of the following side effects:

Shortness of breath due to muscle cramping of the airways (bronchospasms).

Difficulty breathing, shortness of breath or breathlessness (dyspnoea).

Impaired digestion with symptoms of fullness in the upper abdomen, gastric pain, belching, nausea and heartburn (dyspepsia). These side effects are rare (occurring in 1 to 10 in every 10,000 users). Hypersensitivity. This may manifests itself as bronchospasms and dyspnoea (see above) rapid heart rate (tachycardia), itching (pruritus), skin rash with severe itching and small bumps (urticaria) and angioedema.

Headache

Ringing in the ears (tinnitus)

Inflammation of the oral mucous lining (stomatitis)

Diarrhoea

Fever (pyrexia)

Low blood pressure

Abdominal pain

Nausea

Vomiting

These side effects are uncommon (occurring in 1 to 10 in every 1,000 users). If you suffer from gastric or duodenal ulcers or have had these in the past, acetylcysteine may have an unfavourable effect on your gastrointestinal mucous membrane. Consult with your doctor or pharmacist if you notice that the effect of NACSYS 600 mg effervescent tablets is too strong or not strong enough.

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