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What is another name for quercetin?

Quercetin is found in high concentrations in asparagus, red onions, broccoli and buckwheat. Other names for quercetin include: Citrus bioflavonoid, Sophoretin; Meletin; Quercetine; Xanthaurine; Quercetol; Quercitin; Quertine; Flavin.

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Quercetin is one of many flavonoids found in plant pigments, being orange to orange-yellow in color. It is the principal source flavonoid in human nutrition and is commonly used in food processing.[1] Quercetin is found in high concentrations in asparagus, red onions, broccoli and buckwheat. Other names for quercetin include: Citrus bioflavonoid, Sophoretin; Meletin; Quercetine; Xanthaurine; Quercetol; Quercitin; Quertine; Flavin.[2][3] Quercetin affects immunity and inflammation by acting mainly on leukocytes and targeting many intracellular signaling kinases and phosphatases, enzymes and membrane proteins often crucial for cellular specific function.[4][5]

Food sources [ edit | edit source ]

Quercetin can be found in many foods including red onions, red wine, onions, green tea, apples, asparagus, berries, broccoli and Brassica vegetables, kale, ginkgo biloba, St. John's Wort, American elder, and buckwheat tea.[1][6]

Health uses [ edit | edit source ]

Quercetin supplements are often promoted for

However, many of these uses have weak evidence supporting them, and for some uses there is evidence that quercetin supplementation do not improve symptoms.[1]

Quercetin is also taken by athletes to increase endurance and improve performance.[1]

Quercetin is a potent antioxidant.[5] Most of the information on flavonoids concerns quercetin because with only sight changes to the backbone of flavones and subtle cell behavior mechanisms and responsiveness, flavoinoids can be modulating, biphasic and exert regulatory action on immunity and inflammation. Only a few flavones and flavonols have been assayed mainly due to chemical similarity to quercetin.[4] The US FDA has issued warning letters to manufacturers of supplements containing quercetin to withdraw health benefit claims and emphasize that quercetin is not a defined nutrient nor an antioxidant, cannot be assigned a dietary content level and is not regulated as a drug to treat any human disease.[8] The European Food Safety Authority evaluated possible health claims associated with consumption of quercetin, and found that no cause-and-effect relationship established for any physiological effect in human health or diseases.[9]

Chronic fatigue syndrome [ edit | edit source ]

Quercetin's antioxidant and anti-inflammatory properties are thought to be important in resolving the pathophysiology of ME/CFS. Additionally, a 2009 study by J. Mark Davis, et al. (2008)[10] showed markers of mitochondrial biogenesis in mouse skeletal muscle and brain, and on endurance exercise tolerance after a week of quercetin in their food.

Luteolin is another flavonoid antioxidant which is common place.

Flavonoids are believed to be poorly absorbed due to bring rapidly metabolized and excreted. There remains no evidence that polyphenols (of which flavonoids are subset of) have any relevance on the body. Quercetin acts to inhibit the enzyme monoamine oxidase (MAO), an enzyme that breaks down the mood-influencing neurotransmitters serotonin, dopamine and norepinephrine,[6] although clinical trials in humans are lacking.

See also [ edit | edit source ]

Learn more [ edit | edit source ]

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What are the side effects of too much quercetin?

Common side effects of quercetin include: Headache (oral use) Numbness and tingling (oral use) Shortness of breath (intravenous use) Nausea and vomiting (intravenous use) Kidney damage (intravenous use greater than 945 mg/m2)

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Quercetin?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

Quercetin has no known severe interactions with other drugs.

Serious Interactions of quercetin include: everolimus topotecan

Quercetin has moderate interactions with at least 60 different drugs.

Mild interactions of quercetin include: alvimopan armodafinil ciprofloxacin fexofenadine fleroxacin gemifloxacin levofloxacin loratadine moxifloxacin norfloxacin ofloxacin This information does not contain all possible interactions or adverse effects. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions, concerns, or for more information about this medicine.

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