What does quercetin do for sinuses?

Quercetin. Quercetin is a flavonoid. In test tubes, it inhibits the production and release of histamine, which causes allergy symptoms such as a runny nose and watery eyes.

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Treatment of sinusitis aims to reduce inflammation and clear your sinuses. Your doctor may prescribe antibiotics or corticosteroids. Lifestyle changes, such as using a humidifier or irrigating your nasal passages with salt water, may also help. Several dietary supplements and herbs may help prevent colds and flu, shorten their duration, or work together with antibiotics to treat your infection and support your immune system.

Lifestyle

These measures can help reduce congestion in your sinuses:

Using a humidifier

Using a saline nasal spray

Inhaling steam 2 to 4 times per day (for example, sitting in the bathroom with the shower running)

Quickly treating allergic and asthma attacks

Medications

Antibiotics. Your health care provider may prescribe antibiotics if your symptoms suggest you have a bacterial infection. However, antibiotics should not be prescribed for mild-to-moderate sinusitis within the first week of the illness. To treat acute sinusitis, you may take from 10 to 14 days of antibiotics. Treating chronic sinusitis may take longer, usually 3 to 4 weeks. Nasal corticosteroids. These prescription sprays reduce inflammation of the nose and help relieve sneezing, itching, and runny nose. They are most effective at reducing symptoms, although it can take from a few days to a week after you start using them to see improvement.

Beclomethasone (Beconase)

Fluticasone (Flonase)

Mometasone (Nasonex)

Triacinolone (Nasacort)

Antihistamines. Antihistamines are available in both oral and nasal spray forms, and as prescription drugs and over-the-counter (OTC) remedies. OTC antihistamines are short acting and can relieve mild-to-moderate symptoms. All work by blocking the release of histamine in your body. OTC antihistamines. Include diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), and clemastine (Tavist). These older antihistamines can cause sleepiness. Loratadine (Claritin), a newer antihistamine, does not cause drowsiness. All OTC antihistimines are short acting and can relieve mild-to-moderate symptoms. Include diphenhydramine (Benadryl), chlorpheniramine (Chlor-Trimeton), and clemastine (Tavist). These older antihistamines can cause sleepiness. Loratadine (Claritin), a newer antihistamine, does not cause drowsiness. All OTC antihistimines are short acting and can relieve mild-to-moderate symptoms. Prescription antihistamines. Include fexofenadine (Allegra) and cetrizine (Zyrtec). These medications are longer acting than over-the-counter antihistamines and are usually taken once a day. Decongestants. Many OTC and prescription decongestants are available in tablet or nasal spray form. They are often used with antihistamines. Oral and nasal decongestants include Sudafed, Actifed, Afrin, Neo-Synephrine. Some decongestants may contain pseudoephedrine, which can raise blood pressure. People with high blood pressure or an enlarged prostate should not take drugs containing pseudoephedrine. Nasal decongestants can cause "rebound congestion," where the nasal passages swell. Avoid using nasal decongestants for more than 3 days in a row, unless instructed by your health care provider, and do not use them if you have emphysema or chronic bronchitis.

Surgery and Other Procedures

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For chronic sinusitis that does not respond to medication, your doctor may recommend endoscopic sinus surgery, which may be done to remove polyps or bone spurs. Enlarging the sinus opening is also sometimes recommended. A newer procedure called balloon rhinoplasty involves inserting a balloon inside the sinus cavity and then inflating it. Your health care provider may suggest other alternatives.

Nutrition and Dietary Supplements

Because supplements may have side effects, or interact with medications, you should take them only under the supervision of a knowledgeable health care provider. Bromelain. Several studies suggest that bromelain, an enzyme derived from pineapples, may help reduce inflammation and swelling and relieve symptoms of sinusitis. However, not all studies show a benefit. Bromelain is often combined with the flavonoid quercetin, which may act as an antihistamine. Bromelain may increase the risk of bleeding, so people who take anticoagulants (blood thinners) should not take bromelain without talking to their doctor first. Taking bromelain with ACE inhibitors may cause a drop in blood pressure (hypotension). Several studies suggest that bromelain, an enzyme derived from pineapples, may help reduce inflammation and swelling and relieve symptoms of sinusitis. However, not all studies show a benefit. Bromelain is often combined with the flavonoid quercetin, which may act as an antihistamine. Bromelain may increase the risk of bleeding, so people who take anticoagulants (blood thinners) should not take bromelain without talking to their doctor first. Taking bromelain with ACE inhibitors may cause a drop in blood pressure (hypotension). Quercetin. Quercetin is a flavonoid. In test tubes, it inhibits the production and release of histamine, which causes allergy symptoms such as a runny nose and watery eyes. However, there is not much evidence that quercetin works the same way in humans. More studies are needed. Some people report that water-soluble quercetin, such as quercietin methyl chalcone, may work best. Quercetin can potentially interact with some prescription medicaions, including antibiotics. Quercetin is a flavonoid. In test tubes, it inhibits the production and release of histamine, which causes allergy symptoms such as a runny nose and watery eyes. However, there is not much evidence that quercetin works the same way in humans. More studies are needed. Some people report that water-soluble quercetin, such as quercietin methyl chalcone, may work best. Quercetin can potentially interact with some prescription medicaions, including antibiotics. Probiotics (Lactobacillus). Probiotics, or "friendly" bacteria, may be helpful if you are taking antibiotics for sinusitis. They may also reduce your chances of developing allergies. Probiotics may not be appropriate for people who are extremely immunocompromised or who take immunosuppresent drugs. Talk to your provider. Probiotics, or "friendly" bacteria, may be helpful if you are taking antibiotics for sinusitis. They may also reduce your chances of developing allergies. Probiotics may not be appropriate for people who are extremely immunocompromised or who take immunosuppresent drugs. Talk to your provider. N-acetylcysteine (NAC). NAC is a modified form of a dietary amino acid that works as an antioxidant in the body. It also helps thin mucus. NAC may interact with nitroglycerin, use to treat chest pain (angina). NAC may not be appropriate for certain people with asthma and/or bleeding disorders.

Herbs

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The use of herbs is a time-honored approach to strengthening the body and treating disease. Herbs, however, can trigger side effects and can interact with other herbs, supplements, or medications. For these reasons, you should take herbs only under the supervision of a health care provider. Sinupret. A proprietary formulation containing Sambucus nigra (European elder), Rumex acetosa (common sorrel), Primula veris (cowslip), Verbena officinalis (European vervain), Gentiana lutea (gentian). Several studies suggest that Sinupret may be effective in relieving symptoms of sinusitis. The herbs it contains may work by thinning mucus and helping the sinuses drain. They may also help strengthen the immune system. Ask your doctor if sinupret is right for you.

Acupuncture

Although studies are few and have found conflicting results, some people may find that acupuncture helps relieve symptoms of sinusitis. Acupuncturists usually describe sinusitis as "dampness," which creates inflammation and congestion in the mucus membranes. This dampness is cleared by strengthening the spleen meridian, and by working with the stomach meridian. Practitioners often perform needling therapy or moxibustion (a technique in which the herb mugwort is burned over specific acupuncture points) for this condition. A 2009 double-blind, randomized, controlled study found that acupuncture significantly improved nasal air flow and decreased congestion in participants with chronic sinusisits. These benefits also increased 30 minutes after treatment.

Chiropractic

Some practitioners suggest chiropractic care may decrease pain and improve sinus drainage for some people.

Homeopathy

Few studies have examined the effectiveness of specific homeopathic remedies. In one study of homeopathy for sinusitis, more than 80% of the 119 participants had significant improvement in their symptoms after taking the homeopathic remedy for 2 weeks without antibiotics or other medications. Professional homeopaths may recommend one or more of the following treatments for sinus congestion based on their knowledge and clinical experience. Before prescribing a remedy, homeopaths take into account a person's constitutional type. In homeopathic terms, a person's constitution is their physical, emotional, and intellectual makeup. An experienced homeopath assesses all of these factors when determining the most appropriate remedy for a particular individual.

mountsinai.org - Sinusitis Information | Mount Sinai - New York