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Should I take adrenal cortex on an empty stomach?

You'll usually take them 2 or 3 times a day. Take the tablets with or just after a snack or meal. This is so they do not upset your stomach.

nhs.uk - Hydrocortisone tablets: a steroid used for treating adrenal gland problems

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Hydrocortisone tablets come as standard or slow-release tablets. They are also available as a soluble tablet that you dissolve in water before use. Your pharmacist or doctor will tell you which type of hydrocortisone tablets you're taking and how to take them. Always follow the instructions that come with your medicine.

Dosage

Hydrocortisone comes as 5mg, 10mg and 20mg tablets.

If you take hydrocortisone tablets for hormone replacement the usual dose is 20mg to 30mg a day, split into 2 doses. The first dose in the morning may be larger than the second dose in the evening. If you have an infection, or if you need to have dental treatment or an operation, you'll probably need to take a higher dose for a while.

How to take standard tablets

Standard tablets start to release the medicine into your body as soon as you swallow them. You’ll usually take them 2 or 3 times a day. Take the tablets with or just after a snack or meal. This is so they do not upset your stomach.

How to take slow-release tablets

Some hydrocortisone tablets are slow release (also known as modified release). These tablets release the medicine into your body gradually throughout the day.

You’ll usually take slow-release tablets once a day.

Take them in the morning, around half an hour before breakfast. Swallow them whole. Do not break or crush the tablets, as they will not work properly. Do not eat grapefruit or drink grapefruit juice while you're being treated with hydrocortisone tablets. Grapefruit can change the way hydrocortisone works and increases the risk of side effects.

How to take soluble tablets

Some hydrocortisone tablets need to be dissolved in at least 50ml of water immediately before swallowing. Make sure you swallow all of the liquid, otherwise you may not get all of the dose. The hydrocortisone starts to be absorbed as soon as the liquid is swallowed. You’ll usually take soluble tablets 3 times a day. Take the tablets with or just after a snack or meal. This is so they do not upset your stomach.

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What if I forget to take a tablet?

Try to remember to take your tablets every day. Regularly missing doses can make you feel unwell. If you forget to take a dose, take it as soon as you remember. If you do not remember until the next dose is due, skip the missed dose.

Never take 2 doses to make up for a forgotten one.

If you often forget to take your tablets, it may help to set an alarm to remind you. You could also ask your pharmacist for advice on other ways to remember your medicine.

Will the dose I take go up or down?

Your doctor may increase or decrease your dose of hydrocortisone during the first weeks or first month of your treatment until your health problem is stable. You may need a bigger dose for a while if you are unwell with other health problems such as an infection, or if you need to have an operation. You may need a short, very high dose of hydrocortisone if you have Addison's disease and your cortisol levels drop suddenly. This is a medical emergency called an adrenal crisis. If you have been diagnosed with adrenal insufficiency you will need to carry a steroid emergency card with you. If you need emergency treatment, this will tell medical staff about your condition and how to treat you.

What if I take too much?

Taking too many hydrocortisone tablets as a one-off is unlikely to harm you. If you're worried, talk to your doctor or pharmacist. If you take too much hydrocortisone for more than a few days, it could harm your health. Talk to your doctor as soon as possible.

nhs.uk - Hydrocortisone tablets: a steroid used for treating adrenal gland problems

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