Smoothy Slim
Photo by RODNAE Productions Pexels Logo Photo: RODNAE Productions

How do you test for histamine levels?

Instead of a blood test, a histamine test performed on urine collected over a 24-hour period may be ordered instead to evaluate histamine production over a longer time frame. In some cases, the metabolite N-methylhistamine may be measured in urine instead of histamine.

Does drinking a lot of water make you look younger?
Does drinking a lot of water make you look younger?

As it turns out, one of the best-kept secrets for healthier, younger-looking skin is as easy to find as turning the tap. Water makes up a large...

Read More »
What happens if I don't eat after a workout?
What happens if I don't eat after a workout?

If you don't eat after a workout, it can lead to problems such as low energy, dehydration, poor muscle recovery, low electrolyte levels and low...

Read More »
Tasty juice “eats through” 54lbs of thick flab
Tasty juice “eats through” 54lbs of thick flab

This effective juice jolts the metabolism, boosts energy and burns fat all day.

Learn More »

Histamine is a substance that is released from specialized cells called mast cells when they are activated, often as part of an allergic immune response. This test measures the amount of histamine in the blood or urine. Mast cells are large tissue cells found throughout the body. They are present mainly in the skin, the lining of the intestine and air passages, and the bone marrow. Mast cells are part of the body’s normal response to injury as well as allergic (hypersensitivity) responses. They contain granules that store a number of chemicals, including histamine and tryptase, which are released when mast cells become activated. Histamine is responsible for many of the symptoms in persons with allergies. Concentrations of histamine in the blood and urine are normally very low. Significant increases can be seen in people with a severe allergic reaction and in those with a disorder in which the number of mast cells increase (proliferate) and/or activate without apparent allergies. The activation of many mast cells is associated with a severe form of acute allergic reaction termed anaphylaxis, which can cause hives (blisters on the skin), reddening of the skin (flushing), low blood pressure, severe narrowing of the air passages, and even death. With anaphylaxis, histamine concentrations in the blood increase rapidly, rising within 10 minutes of the start of symptoms and returning to normal within about 30 to 60 minutes. This increased production is also reflected a short time later in the urine as histamine and its primary metabolite, N-methylhistamine, are excreted. Histamine and tryptase levels may be persistently increased in people with mastocytosis. This rare condition is associated with abnormal proliferation of mast cells and their infiltration and accumulation in the skin (cutaneous mastocytosis) and/or in organs throughout the body (systemic mastocytosis).

How is the sample collected for testing?

A blood sample is obtained by inserting a needle into a vein in the arm. For a 24-hour urine collection, all of the urine should be saved for a 24-hour period. It is best to keep the sample in a cool, dark place such as a refrigerator.

Is any test preparation needed to ensure the quality of the sample?

If anaphylaxis is suspected, it is important to collect the sample very soon after the beginning of symptoms. If testing is done for other conditions, you may be instructed to refrain from taking antihistamine and other medications. This should be discussed with your health care practitioner.

Why is my belly fat so stubborn?
Why is my belly fat so stubborn?

Abdominal fat cells tend to have the receptors that do not allow for easy release of fat; this is the key to why belly fat is so resistant to...

Read More »
Is Onion good for you?
Is Onion good for you?

Onions contain antioxidants and compounds that fight inflammation, decrease triglycerides, and reduce cholesterol levels — all of which may lower...

Read More »
Fizzy juice “eats through” 59lbs of stubborn fat
Fizzy juice “eats through” 59lbs of stubborn fat

This effective juice jolts the metabolism, boosts energy and burns fat all day.

Learn More »

Does vitamin B12 increase histamine?

A vitamin B12 injection also releases (a lot of) histamine from the mast cells. When there is a lot of free histamine in our body, there is an elevated histamine level.

Histamine is a substance that plays an important role in a large number of processes in our bodies. An example of this is with our sleep-wake rhythm and the functioning of our immune system and nervous system. Our body makes its own histamine and stores it largely in so-called ‘mast’ cells. These specialized cells are located in tissues that are in contact with the outside world, such as the skin, lungs and gastrointestinal tract. Histamine can be released from the mast cells during an allergic reaction and it enters the blood. Medications, such as certain painkillers (ibuprofen and morphine, among others), antibiotics and drugs for high blood pressure, can also release histamine. A vitamin B12 injection also releases (a lot of) histamine from the mast cells. When there is a lot of free histamine in our body, there is an elevated histamine level. Histamine occurs naturally in many plant and animal products. In addition to the body’s own histamine, we also ingest it through our diet. In particular, fermented and mature foods contain a lot of histamine. Histamine from our food does not normally enter our bloodstream because the Diamine Oxidase enzyme (DAO) breaks it down in our intestines. With histamine intolerance, histamine is not broken down properly or at all, so histamine levels can become too high. Histamine levels that are too high can cause a variety of symptoms, such as itching, headaches and intestinal discomfort. The most common cause of histamine intolerance is a deficiency of the DAO enzyme, which prevents the histamine from your food from being broken down properly and ending up in your blood.

Are bamboo cups BPA free?
Are bamboo cups BPA free?

This helps ensure the bamboo cups are both durable and suitable for the high temperatures required of them with coffee and tea. Printed Bamboo...

Read More »
Is cinnamon good for health?
Is cinnamon good for health?

Cinnamon contains antioxidants, which are a healthy component of the diet that help neutralize free radicals, preventing them from damaging cells...

Read More »
Traditional “juice” activates 24/7 fat-burning
Traditional “juice” activates 24/7 fat-burning

A scrumptious morning smoothy based on the diets of among the healthiest, longest-living hamlet in the world.

Learn More »
What foods cause puffy face?
What foods cause puffy face?

Avoid eating at night ramen. sushi. processed meats like ham, bacon, and salami. milk. cheese. chips. pretzels. french fries. More items...

Read More »
7-second natural hack eats through 64lbs of belly flab
7-second natural hack eats through 64lbs of belly flab

This effective juice jolts the metabolism, boosts energy and burns fat all day.

Learn More »
Does oatmeal cause inflammation?
Does oatmeal cause inflammation?

“Eating whole grain oats can prevent diabetes and lower cholesterol levels, which could prevent cardiovascular disease.” Some studies show that...

Read More »