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Does water fasting increase metabolism?

The latest study to explore the impact of fasting on the human body concludes that it increases metabolic activity more than previously realized and may even impart anti-aging benefits.

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The latest study to explore the impact of fasting on the human body concludes that it increases metabolic activity more than previously realized and may even impart anti-aging benefits. Share on Pinterest A recent study takes a look at how fasting influences metabolism. Studies have shown that intermittent fasting can help certain people lose weight. Although researchers are still debating exactly how effective fasting can be for weight loss, new research hints at other benefits. In rats, for instance, studies show that fasting can increase lifespan. Although exciting, evidence of this in humans has yet to be seen. The most recent study — which the authors have now published in the journal Scientific Reports — takes a fresh look at fasting in humans and provides new insight. “Recent aging studies have shown that caloric restriction and fasting have a prolonging effect on lifespan in model animals,” says first study author Dr. Takayuki Teruya, “but the detailed mechanism has remained a mystery.” In particular, scientists at the Okinawa Institute of Science and Technology Graduate University in Japan examined its impact on metabolism. By understanding the metabolic processes involved, the team hopes to find ways of harnessing the benefits of fasting without the need to go without food for prolonged periods. To investigate, they fasted four volunteers for 58 hours. Using metabolomics, or the measurement of metabolites, the researchers analyzed whole blood samples at intervals during the fasting period. What happens during fasting? As the human body is starved of food, there are a number of distinct metabolic changes that occur. Normally, when carbohydrates are readily available, the body will use them as fuel. But once they are gone, it looks elsewhere for energy. In a process called gluconeogenesis, the body derives glucose from noncarbohydrate sources, such as amino acids. Scientists can find evidence of gluconeogenesis by assessing the levels of certain metabolites in the blood, including carnitines, and butyrate. As expected, after fasting, levels of these metabolites had increased in the participants’ blood. However, the scientists also identified many more metabolic changes, some of which surprised them. For instance, they saw a marked increase in products of the citric acid cycle. The citric acid cycle happens in mitochondria, and its function is to release stored energy. The hike seen in the metabolites associated with this process means that the mitochondria, the fabled powerhouses of the cell, are thrust into overdrive. Another surprise finding was an increase in levels of purine and pyrimidine, which scientists had not yet linked to fasting. These chemicals are a sign of increased protein synthesis and gene expression. This suggests that fasting causes cells to switch up the type and quantity of proteins that they need to function.

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Can you survive on only liquids?

Eating only a full liquid diet can give you enough energy, protein, and fat. But it does not give you enough fiber. Also, you may not get all the vitamins and minerals you need.

You can eat or drink only things that are liquid. You may have these foods and drinks:

Water

Fruit juices, including nectars and juices with pulp

Butter, margarine, oil, cream, custard, and pudding

Plain ice cream, frozen yogurt, and sherbet

Fruit ices and popsicles

Sugar, honey, and syrups

Soup broth (bouillon, consommé, and strained cream soups, but no solids)

Sodas, such as ginger ale and Sprite

Gelatin (Jell-O)

Boost, Ensure, Resource, and other liquid supplements

Tea or coffee with cream or milk and sugar or honey

Ask your doctor or dietitian if you can include these foods in your full liquid diet: Cooked, refined cereals, such as cream of rice, oatmeal, grits, or farina (Cream of Wheat)

Strained meats, like the ones in baby food

Potatoes pureed in soup

Do not eat any kind of cheese, fruit (fresh, frozen, or canned), meat, and cereals that are not on your "OK" list. Also, do not eat raw or cooked vegetables. And, do not eat ice cream or other frozen desserts that have any solids in them or on top, such as nuts, chocolate chips, and cookie pieces. Try having a mix of 5 to 7 of the foods you can eat for breakfast, lunch, and dinner. Liquid foods do not include mashed foods, such as mashed potato or avocado. Eating only a full liquid diet can give you enough energy, protein, and fat. But it does not give you enough fiber. Also, you may not get all the vitamins and minerals you need. So, your doctor may recommend that you take certain vitamins and supplements. This diet is safe for people with diabetes, but only when they are followed closely by their doctor.

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