Can vitamin C cause kidney failure?

Conclusions: High dose vitamin C can cause severe and potentially irreversible renal impairment due to oxalate nephropathy and awareness needs to be raised in conventional and alternative medical communities as well as the general population of the danger associated with this treatment.

anzsnasm.com - HIGH DOSE VITAMIN C (ASCORBIC ACID) CAUSING RENAL FAILURE ...

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B DOUCET1,2, E NOBLE1, N GRAY1,2

1Department of Nephrology, Sunshine Coast University Hospital, Birtinya, Australia, 2School of Medicine, University of Queensland, Brisbane, Australia Background: Vitamin C (ascorbic acid) is commonly prescribed for complementary and alternative medical indications or used as a personal health choice. Intravenous vitamin C treatments are gaining popularity in the alternative management of malignant conditions despite the lack of evidence to suggest benefit. The risks of high dose vitamin C may not be appreciated by prescriber or recipient. One of the most devastating adverse effects of high dose vitamin C is oxalate nephropathy. Case Report: We report two cases of vitamin C induced oxalate nephropathy. A 67 year old male with metastatic oesophageal cancer underwent high dose intravenous vitamin C treatment through a registered Australian medical practitioner for treatment of malignancy. He presented to hospital with anuric renal failure requiring urgent haemodialysis. Serological and imaging investigations revealed no cause of renal impairment. He did not respond to fluid resuscitation and remains dialysis dependant. An 80 year old female presented to hospital with malaise. Investigations revealed severe kidney injury on the background of consuming multiple self-initiated alternative medications, several containing vitamin C. No other cause of renal impairment was identified and vitamin C supplements were ceased. Renal function has improved close to baseline over a one month period. Renal biopsy in both cases revealed severe tubular injury and extensive tubular oxalate crystal deposition consistent with oxalate nephropathy. Conclusions: High dose vitamin C can cause severe and potentially irreversible renal impairment due to oxalate nephropathy and awareness needs to be raised in conventional and alternative medical communities as well as the general population of the danger associated with this treatment.

Biography:

Brian Doucet is a second year Nephrology advanced trainee from Queensland. He has previously presented at the ANZSN ASM in 2014 and 2017.

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What is the best age to become mother?

Experts say the best time to get pregnant is between your late 20s and early 30s. This age range is associated with the best outcomes for both you and your baby. One study pinpointed the ideal age to give birth to a first child as 30.5. Your age is just one factor that should go into your decision to get pregnant.

healthline.com - Childbearing Age: What's Ideal and What Are the Risks? - Healthline

What’s the childbearing age?

Technically, women can get pregnant and bear children from puberty when they start getting their menstrual period to menopause when they stop getting it. The average woman’s reproductive years are between ages 12 and 51. Your fertility naturally declines as you get older, which could make it harder for you to conceive. And starting a family later in life could pose greater risks for pregnancy complications. Experts say the best time to get pregnant is between your late 20s and early 30s. This age range is associated with the best outcomes for both you and your baby. One study pinpointed the ideal age to give birth to a first child as 30.5. Your age is just one factor that should go into your decision to get pregnant. You also need to consider your emotional and financial readiness to start a family. That timing is unique for each woman.