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Are liquid fasts healthy?

Liquid diets that only allow you to drink certain juices, teas or other beverages are not good long-term weight loss strategies. Solid foods contain many necessary nutrients. Therefore, it is not recommended to stay on a diet consisting of liquids alone in the long term.

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Liquid diets are nutrition programs that require you to get either some, most or all of your daily calories from liquids, rather than solid foods. While there are many liquid diets, most can be grouped into one of the following categories.

Meal Replacements

Some liquid diets involve meal replacement shakes, which are consumed in place of solid foods. Numerous companies sell these shakes for weight loss purposes. Meal replacement shakes are often lower in calories than typical meals. They can replace one or multiple meals each day ( 1 ). They are designed to contain all the nutrients your body needs to function, including macronutrients (protein, carbs and fat) and micronutrients (vitamins and minerals) ( 2 ). Some weight loss programs use these shakes to account for your entire calorie intake for up to several months ( 3 ).

Detox Diets and Cleanses

Other liquid diets include detox diets or cleanses, which require the consumption of certain juices or drinks that supposedly remove toxic substances from your body ( 4 ). Examples of these diets include the Master Cleanse, long-term water fasting and various juicing programs. Unlike meal replacement shakes, these programs typically rely on a few natural ingredients like juices from certain fruits and vegetables and other botanical ingredients. Because of this, these diets may not contain all the nutrients your body needs.

Medically Prescribed Liquid Diets

Clear liquid and full liquid diets are examples of diets that are medically prescribed for specific health reasons. As the name implies, clear liquid diets only allow the consumption of clear liquids, such as water, apple juice, tea, certain sports drinks and broths (5). These diets may be prescribed before or after certain surgeries or if you have digestive problems. Full liquid diets are prescribed for similar reasons, but they are less restrictive than clear liquid diets. They allow most beverages, as well as foods that become liquid at room temperature, such as popsicles, Jell-O, pudding, syrups and some shakes (6). Summary Liquid diets replace some or all food with beverages. There are several types, including meal replacement programs, cleanses and medically prescribed liquid diets.

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Does fasting affect the liver?

“We know that fasting can be an effective intervention to treat disease and improve liver health.

Australian researchers have used state-of-the-art analytical tools to understand how intermittent fasting works on the liver to help prevent disease. The findings will help medical scientists working in cancer, cardiovascular and diabetes research develop new interventions to lower disease risk and discover the optimum intervals for fasting. In experiments with mice, researchers led by Dr Mark Larance at the University of Sydney identified how every-other-day fasting affected proteins in the liver, showing unexpected impact on fatty acid metabolism and the surprising role played by a master regulator protein that controls many biological pathways in the liver and other organs. “We know that fasting can be an effective intervention to treat disease and improve liver health. But we haven’t known how fasting reprograms liver proteins, which perform a diverse array of essential metabolic functions,” said Dr Larance, a Cancer Institute of NSW Future Research Fellow in the Charles Perkins Centre and School of Life and Environmental Sciences at the University of Sydney. “By studying the impact on proteins in the livers of mice, which are suitable human biological models, we now have a much better understanding of how this happens.” In particular, the researchers found that the HNF4-(alpha) protein, which regulates a large number of liver genes, plays a previously unknown role during intermittent fasting. “For the first time we showed that HNF4-(alpha) is inhibited during intermittent fasting. This has downstream consequences, such as lowering the abundance of blood proteins in inflammation or affecting bile synthesis. This helps explain some of the previously known facts about intermittent fasting,” Dr Larance said.

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